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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6859 | I-BRD9 | GSK602 | Epigenetic Reader Domain |
I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3. | |||
T62024 | GSK852 | ||
GSK852 is a potent, second bromodomain (BD2)-selective, bromo and extra-terminal domain (BET) inhibitor with pIC50 of 7.9. | |||
T70702 | JQ1-Acid HCl | ||
(+)-JQ-1 carboxylic acid is a potent bromodomain and extra terminal domain (BET) inhibitor. (+)-JQ-1 carboxylic has potential to be used as a precursor to synthesize PROTACs and other conjugates. | |||
T39634 | GSK097 | ||
GSK097 is a highly potent and selective inhibitor of the second bromodomain (BD2) found in bromodomain and extra-terminal domain (BET) proteins. It exhibits a remarkable 2000-fold selectivity for BD2 over BD1, as indicat... | |||
T36800 | EN219 | ||
EN219 is a synthetic recruiter of the E3 ubiquitin ligase RNF114.1It binds to cysteine 8 (C8) in the intrinsically disordered region of RNF114 (RNF114-C8; IC50= 470 nM) and inhibits RNF114-induced autoubiquitination and ... |